Phase 53 · Protein & Peptide Tools
Bispecific & Multispecific Antibody Architecture Designer
Build transparent protein-sequence architectures for tandem scFv, dual-VHH, IgG-scFv and IgG-VHH research constructs using user-supplied binding domains, linkers and constant regions.
Architecture Tandem scFv / BiTE-like Dual VHH IgG-scFv fusion IgG-VHH fusion
Binder A scFv orientation VH-VL VL-VH
Binder B scFv orientation VH-VL VL-VH
Binder A
Binder B
Optional IgG constant regions
Heavy constant sequence
Light constant sequence
Load tandem scFv demo Build architecture
Ready.
Scientific guardrails
No binding or simultaneous target engagement is predicted.
No chain-pairing correction is designed.
No knob-into-hole, CrossMab or common-light-chain engineering is added.
Signal peptides are not added automatically.
Linker choice remains an experimental design decision.
“Bispecific” here describes the intended sequence architecture only. Functional bispecificity must be demonstrated experimentally.
Architecture result
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